Cover Feature: Chemical Proteomics Reveals Protein Tyrosination Extends Beyond the Alpha‐Tubulins in Human Cells (ChemBioChem 23/2022)

Microtubules are dynamic structures regulated by post-translational modifications called a tubulin code. The pictured jester's cap ‘n’ bells resembles disassembling microtubules—a catastrophe—with the illustrating C-terminal tyrosine on tubulins. One is replaced our chemical proteomics probe, which being attached tubulin-tyrosine ligase. juggling amino acids of proteins animate tyrosination cycle. background fluorescence imaging picture showing distribution tyrosination-probe labelled in neuroblastoma cells. More information can be found Research Article D. Makarov and P. Kielkowski.